Duane Tolbert Gish is an American biochemist and a prominent member of the creationist movement. Gish is a former vice-president of the Institute for Creation Research (ICR) and the author of numerous publications on the subject of scientific creationism. Gish has been called "creationism's T.H. Huxley" for the way he "relished the confrontations" of formal debates with prominent evolutionists, usually held on university campuses."

He holds a Ph.D. in biochemistry from the University of California, Berkeley.

He spent 18 years in biochemical and biomedical research at Cornell University Medical College, the Virus Laboratory of the University of California, Berkeley, and The Upjohn Company, Kalamazoo, Michigan. He is the author or co-author of numerous technical articles in his field and a well-known author and lecturer on creation/evolution.